Stop saying “delta plus”. This does not mean anything.


At the same time, the name delta comes from the WHO system, which aims to simplify genomics for the public. If it thinks they might be particularly interesting, it will name the relevant covid samples. There are currently eight families with Greek letters, but before there is evidence that the new subline of the first delta strain behaves differently from its parents, the WHO considers them all deltas.

“Delta plus” adopted the name of the World Health Organization and mixed it with Pango’s pedigree information. This does not mean that the virus is more dangerous or worrying.

“When people see a new Pango name, they will be very anxious. But we shouldn’t be upset about discovering new variants. All the time, we will see new variants appear without any different behavior,” cloth Rito said. “If we have evidence that a new bloodline is more threatening, the WHO will give it a new name.”

Tracking evolution

“For genomics scientists like me, I want to know what variants we see,” said Kelsey Florek, a senior genomics and data scientist at the Wisconsin Public Health Laboratory. “For the wider public, this has no real impact. Classifying them all as deltas is enough to communicate with policymakers, public health, and the public.”

Fundamentally speaking, virus evolution is the same as any other type of evolution. When a virus spreads through the body, it replicates itself, which usually involves small errors and changes. Most of them are dead ends, but occasionally, a copy with errors will replicate enough in one person to spread to others.

This week, scientists divided the “children” of the Delta into 12 families to better track small-scale local changes. This does not mean that the virus itself has suddenly changed.

As the virus spreads from person to person, it accumulates these small changes, allowing scientists to track transmission patterns—just like we can look at the human genome and determine which people are related. But in viruses, most genetic changes have no effect on how they actually affect individuals and communities.

But genomic scientists still need a way to track the evolution of viruses, whether for basic science or to identify any changes in behavior as early as possible. This is why they pay close attention to delta mode, especially because it spreads so fast. The Pango team continued to divide the descendants of the first delta pedigree B.1.617.2 into subcategories of related cases.

Until recently, it registered 617.2 on its own, plus three “children”, called AY.1, AY.2, and AY.3. This week, the team decided to divide these children into 12 families to better track small-scale local changes-so there are 13 delta variants in total. This does not mean that the virus itself has suddenly changed.

Duncan MacCannell, chief scientific officer of the CDC Office of Advanced Molecular Testing, said: “Especially at the edges, with these emerging mutations, you will be distracted.” “Based on the way these definitions are made and refined, hair can split in different ways. .”

What is important to the public?

It’s worth noting that not all variants with the WHO nickname are equally bad. When the organization names a new family, it also adds a label to tell us how worried we should be.

The lowest level is a Interest variants, Which means it is worth paying attention to; in the middle is a Variations of interest, Just like delta, it has obviously evolved to be more dangerous. Often, variants of interest are given this label because they share a mutation with the variant of interest—they are monitored.


Source link